Eli Lilly Presents 16 Alzheimer's Disease Diagnostic and Therapeutic Research Abstracts at AAIC 2026 (July 12-15) Including P-Tau217 Blood Biomarker Data Presented by Samantha Burnham, PhD Demonstrating Strong Rule-In Performance Comparable to Amyloid PET for Identifying Alzheimer's Disease Pathology in Cognitively Unimpaired Individuals, Supporting a Potentially Scalable Blood-Test Alternative to Specialized Imaging for Future Early-Detection Screening
Eli Lilly (NYSE: LLY) presented 16 Alzheimer's disease diagnostic and therapeutic research abstracts at AAIC 2026 in London (July 12-15), including anchor data on the P-tau217 blood biomarker assay. Samantha Burnham, PhD, senior research scientist at Eli Lilly, presented data showing that P-tau217 blood biomarker assays demonstrated strong rule-in performance for identifying Alzheimer's disease pathology, with results indicating that the assays performed comparably to amyloid PET (positron emission tomography) for identifying pathology in cognitively unimpaired individuals. P-tau217 is a phosphorylated fragment of tau protein released from the brain into the bloodstream during Alzheimer's disease pathology; the fragment can be measured with a standard blood draw rather than requiring the specialized PET imaging or lumbar puncture that current Alzheimer's diagnostics rely on. Blood biomarker tests and amyloid PET agents are not yet indicated for use in cognitively unimpaired individuals, but the results generate support for a potentially scalable, accessible alternative to imaging in future early-detection screening. Lilly's therapeutic AAIC 2026 slate also included updated data on donanemab (Kisunla) and the P-tau217-anchored diagnostic pathway that pairs with amyloid-directed treatment.