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#Chai-Discovery

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STAT News BIO 2026 Day-3 Readout (June 24): New Color on Lilly-Chai Discovery AI Biologics Pact (Chai-2 Zero-Shot Antibody Design + Purpose-Built Lilly Model) and Lilly-Astellas Stalking-Horse Bid for Sangamo Assets in Bankruptcy

STAT News' June 24, 2026 BIO Readout column (Damian Garde, Allison DeAngelis) delivered behind-the-scenes detail on Eli Lilly's January 9, 2026 collaboration with AI startup Chai Discovery for biologics design, plus an update on the Lilly-Astellas joint bid for Sangamo Therapeutics assets in bankruptcy. The Chai Discovery deal deploys the company's Chai-2 zero-shot antibody design model (reportedly achieving double-digit experimental hit rates and full de novo design capability) plus a purpose-built generative AI model trained exclusively on proprietary Lilly data and tailored to Lilly's discovery workflows. Chai closed a $130 million Series B at $1.3 billion valuation in late 2025, eighteen months after launch. On the Sangamo front, Lilly is in line to acquire Sangamo's capsid delivery platform, zinc finger platform, modular integrase platform, and prion disease program ST-506 in the bankruptcy auction; Astellas is positioned to take Fabry disease asset isaralgagene civaparvovec. BIO 2026 runs June 22-25 at the San Diego Convention Center.