Cyclic Peptide Delivery System Makes Oral Insulin Viable
Kumamoto University's DNP cyclic peptide system achieved roughly one-third to nearly half the effectiveness of injected insulin in animal studies — a major advance for oral insulin delivery.
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New Cyclic Peptide Could Replace Insulin Injections With Daily Pills
Kumamoto University researchers developed cyclic peptide D-DNP-V that escorts insulin through the gut, achieving one-third to nearly half the effectiveness of injected insulin in mice.
Cyclic Peptide Platform Enables Oral Insulin With 33-41% Bioavailability
Kumamoto University researchers developed a cyclic peptide (DNP peptide) that enables oral insulin delivery through the intestinal wall — a dramatic improvement that could end the century-long dependence on injections.