Peptide News Digest

#Oral-Semaglutide-25-50-Mg

2 stories

Industry · View digest

Novo Nordisk Previews EASD 2026 Data Package: Wegovy Pill Real-World OCTANE Study, Cardiometabolic Outcomes, and Next-Generation Amylin Candidates for the September 28-October 2 Milan Meeting

Novo Nordisk announced Wednesday September 16, 2026 the outline of its data presentations for the 62nd Annual Meeting of the European Association for the Study of Diabetes (EASD) 2026 in Milan, Italy, September 28 through October 2. Real-world evidence from the OCTANE study will report Wegovy pill (oral semaglutide 25/50 mg) outcomes in adults with overweight or obesity including weight change, treatment switching patterns, and patient-reported outcomes across a large post-launch cohort. Additional EASD abstracts span obesity, type 2 diabetes, cardiovascular disease, kidney disease, and liver-related outcomes. Next-generation amylin candidate presentations include amycretin (long-acting unimolecular GLP-1/amylin dual agonist Phase 2 monotherapy and combination data) and CagriSema (cagrilintide plus semaglutide) follow-through from the earlier Redefine-1 head-to-head miss versus tirzepatide (23% vs 25.5% weight loss at 68 weeks). The EASD cluster also includes AstraZeneca AZD6234 APRICUS amylin data, Zealand-Roche petrelintide ZUPREME-2, and Roche Pharma Day September 28. Novo's Capital Markets Day in London September 21 will precede the EASD meeting by one week.

Industry · View digest

Oral GLP-1 Weekly Prescription Tracker Hits New High: Novo Wegovy Pill Reaches Approximately 183,000 Weekly Total Scripts Per IQVIA Data

The oral GLP-1 launch race entered its ninth month with Novo Nordisk's Wegovy pill (oral semaglutide 25/50 mg for chronic weight management, U.S. launch January 5, 2026) reaching approximately 183,000 weekly total scripts per the most recent IQVIA week ending September 5, 2026 — the highest weekly total since launch. Eli Lilly's Foundayo (orforglipron, once-daily oral small-molecule non-peptide GLP-1 receptor agonist, U.S. launch April 2026) continued its own prescription climb through the same reporting window. Both products are indicated for adults with obesity or overweight with weight-related comorbidities. Wegovy pill's climb reflects continued Medicare Part D coverage expansion following the November 2025 pricing agreement (Ozempic Pill / Wegovy pill at $149/month per the deal) and CMS 2026 formulary guidance. Foundayo pricing on TrumpRx and cash-pay LillyDirect anchors at $149/month at starting doses. The concurrent oral launch trajectories are the largest test to date of oral incretin adoption relative to the established weekly-injectable class dominated by injectable Wegovy and Zepbound.