#Pediatrics

2 stories

Regulatory October 30, 2026 · View digest

FDA Approves Novo Nordisk's Once-Weekly Insulin Awiqli for Children 10 and Older With Type 2 Diabetes

The FDA cleared insulin icodec-abae 700 U/mL, approved for adults in March 2026, to improve blood sugar control in children aged 10 and older with type 2 diabetes. Healio reported the decision rested on the adult ONWARDS trials plus a single-dose study of how the drug moves through the body in children aged 10 to 17. The approval does not cover type 1 diabetes.

Research October 15, 2026 · View digest

Review: Evidence for CGRP Migraine Drugs in Children Rests on One Randomized Trial and a Handful of Real-World Studies

A narrative review published October 14, 2026 in Current Pain and Headache Reports found that the evidence for CGRP-targeting migraine treatments in people under 18 consists of one randomized controlled trial, of fremanezumab (Ajovy) in children aged 6 to 17 with episodic migraine, which showed benefit, plus several small real-world studies. CGRP drugs have been used in adults since 2018, and the authors said trials of other CGRP-targeting drugs in children are still pending.