Peptide News Digest

#Spike-Platform

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Oncopeptides SPiKE Platform: Affibody-Derived NK-Cell Engager Preclinical Data for Multiple Myeloma at AACR 2026

Oncopeptides AB (Nasdaq Stockholm: ONCO) will present preclinical data on its SPiKE platform at AACR 2026, showing synergistic effects when combining an affibody-derived bispecific engager with expanded adaptive NK cells (ADAPT-NK) in a humanized multiple myeloma mouse model. The approach leverages peptide-scaffold targeting to direct NK-cell cytotoxicity at malignant plasma cells in difficult-to-treat cancers.