Dermatology Review Finds 'Ozempic Face' Tracks the Amount of Weight Lost, About 7% of Midface Volume per 10 kg, Not the Drug Itself
A review by a Chung-Ang University dermatologist, published October 14, 2026 in Aesthetic Surgery Journal, pooled 46 reports on facial hollowing and sagging during GLP-1 weight loss. Serial imaging in 20 patients showed a median 9% loss of midface volume, more in superficial than deep fat (11% vs 7%), about 7% per 10 kg of weight lost, and a survey of 1,226 people linked more facial volume loss to greater percentage weight loss. Similar changes follow bariatric surgery, so the author concluded that weight-loss deflation on top of normal aging, not a drug-specific effect, explains most of it, and that evidence for cosmetic treatments is limited.