Semax & Selank Pricing: April 2026
Semax and Selank are Russian nootropic peptides. Russian pharmacy imports from $11 (3mL), US research vendors $44–$134 for nasal sprays. N-acetyl variants last 6–12 hours.
Semax and Selank are two Russian-developed nootropic peptides with decades of domestic clinical use but no FDA approval. They are the most-researched peptides in the Russian nootropic tradition, manufactured by Peptogen Innovative NP and approved as OTC prescription medications in Russia (Semax since 1982, Selank since 2004).
Semax is a 7-amino-acid fragment of ACTH (Met-Glu-His-Phe-Pro-Gly-Pro) used for cognitive enhancement, neuroprotection, and stroke recovery. In Russia it's prescribed at 0.1% strength for general cognitive use and 1% strength for post-stroke/post-surgical recovery.
Selank is a 7-amino-acid synthetic analog of tuftsin (Thr-Lys-Pro-Arg-Pro-Gly-Pro) used for anxiolytic/nootropic effects — providing anxiolysis without sedation or benzodiazepine-like dependence. Onset is 15–30 minutes after nasal administration.
N-Acetyl Amidate variants — NASP (N-Acetyl Semax Amidate) and NASEL (N-Acetyl Selank Amidate) — add N-terminal acetylation and C-terminal amidation to resist enzymatic breakdown. Half-life extends 2–5x; effect duration goes from 2–4 hours (base) to 6–12 hours (amidate), allowing once or twice daily dosing instead of 2–3x daily.
Forms: Nasal spray is the standard delivery route (bypasses the blood-brain barrier via olfactory/trigeminal pathways). Injectable lyophilized powder also available for research.
Typical dosing:
- Semax: 200–600 mcg intranasal, 1–3x daily (600–900 mcg/day total)
- Selank: 200–400 mcg intranasal, 2–3x daily (600–1200 mcg/day)
- NASP/NASEL: Lower frequency due to extended half-life
Regulatory status (April 2026): NOT FDA-approved in the US. NOT a DEA controlled substance. NOT on the FDA 503A Category 1 bulk substances list — US compounding pharmacies offering them operate in a gray zone. Legal to buy and possess as research chemicals. Personal import of Russian pharmaceutical-grade product is permitted under FDA's 90-day supply rule. Insurance does not cover these peptides.
Russian Pharmacy Imports (Peptogen, Pharmaceutical-Grade)
The pharmaceutical-grade Russian product from Peptogen Innovative NP — the same formulation prescribed in Russia for decades. Shipped from Russia with 3–4 week delivery. FDA generally permits 90-day supply personal imports.
| Channel | Price | Source |
|---|---|---|
| Ru-Pills (Semax 0.1%, 3mL) | €10.49 (~$11) | Ru-Pills |
| Ru-Pills (Selank 0.15%, 3mL) | €16.83 (~$18) | Ru-Pills |
| RxEli (Semax 0.1%, 3mL) | From $30 | RxEli |
| Ballwool (Semax 0.1%, 3mL) | $38 | Ballwool |
| Cosmic Nootropic (Semax 0.1% / 1% / Selank 0.15%) | Contact for pricing | Cosmic Nootropic |
US Clinics & Telehealth
US clinical access is sparse. Most telehealth platforms do not offer Semax or Selank since they're not FDA-approved and not on the 503A bulk list. A small number of clinics and specialty telehealth providers offer them.
| Channel | Price | Source |
|---|---|---|
| Concierge MD (Semax/Selank Injection) | $399/mo subscription | Concierge MD |
| Iowa IV (Monthly Longevity Program) | Contact for pricing | Iowa IV |
| Neuron Medical (Thousand Oaks, CA) | Contact for pricing | Neuron Medical |
US Compounding Pharmacies (Rx Required)
Limited US footprint — Semax and Selank are not on the FDA Category 1 allowed-for-compounding list, so 503A pharmacies offering them operate in a gray area. Pricing is HCP/Rx-gated.
| Channel | Price | Source |
|---|---|---|
| Spectrum Medical (Kalm Blend — Semax 5mg / Selank 5mg) | Contact via provider | Spectrum Medical |
| Simon's Compounding (Selank-Semax Nasal Spray) | Contact via provider | Simon's Compounding |
| Restore Pharmacy (Semax Nasal Spray) | Contact via provider | Restore Pharmacy |
Research Vendors — Base Semax & Selank (Research Use Only)
Research-grade Semax and Selank sold for in-vitro research only. Available as lyophilized vials for reconstitution and as pre-made nasal sprays.
| Channel | Price | Source |
|---|---|---|
| Battle Born Research (Selank 5mg Vial) | $35/vial | Battle Born Research |
| Core Peptides (Selank 10mg Vial) | $52/vial | Core Peptides |
| Core Peptides (Semax 25mg Vial) | $63/vial | Core Peptides |
| SwissChems (Semax 30mg Vial) | $73.95/vial | SwissChems |
| Limitless Biotech (Semax Nasal Spray, 30mg/10mL) | $76.99 | Limitless Biotech |
| PowerPeptides (Selank Nasal Spray, 10mg) | $98.99 | PowerPeptides |
| Pure Bio Labs (Semax Nasal Spray, 50mg/30mL) | $119 | Pure Bio Labs |
| Pure Bio Labs (Selank TP-7 Nasal Spray, 40mg/40mL) | $119 | Pure Bio Labs |
Research Vendors — N-Acetyl Amidate Variants (Research Use Only)
N-Acetyl Semax Amidate (NASP) and N-Acetyl Selank Amidate (NASEL) are enzymatically stabilized versions with 2–5x longer half-life. Effect duration extends to 6–12 hours vs. 2–4 hours for base peptides, allowing less frequent dosing.
| Channel | Price | Source |
|---|---|---|
| Physiopep (NASP Nasal Spray, 10mg) | From $44.95 | Physiopep |
| Limitless Biotech (N-Acetyl Selank Spray, 10mL) | $50.99–$70.39 | Limitless Biotech |
| Iron Mountain Labz (NASP Nasal Spray, 10mL) | $55.66–$122.87 | Iron Mountain Labz |
| BioLongevity Labs (NASP 20mg Vial) | $64.97/vial | BioLongevity Labs |
| Limitless Biotech (NASP Nasal Spray, 30mg) | $84.99 | Limitless Biotech |
| BioLongevity Labs (NASEL 20mg Vial) | $134.97/vial | BioLongevity Labs |